Effects of ventromedial hypothalamic lesions on hunger-motivated behavior in rats.
نویسندگان
چکیده
Effects of ventromedial hypothalamic lesions on hunger motivated behavior in rats " (1970). Retrospective Theses and Dissertations. Paper 4330. 1970 Signature was redacted for privacy.
منابع مشابه
VENTROMEDIAL HYPOTHALAMIC NUCLEI AND FEEDING BEHAVIOR
The role of the ventromedial nuclei of the hypothalamus (VMN) in food behavior was studied in adult male rats, allocated in 3 groups: control, sham and lesioned. Electrolytic lesions were induced stereotaxically (1.2 mA, 15 sec). Results revealed a significant decrease (p<O.05) in body weight (BW) and food intake (FI) in the order of lesioned <sham <control during the fIrst week. However, ...
متن کاملNaloxone-induced suppression of food intake in normal and hypothalamic obese rats.
Intraperitoneal injections of naloxone hydrochloride (1, 2, 4, and 8 mg/kg) suppressed food intake in both normal and hypothalamic obese rats maintained on a 4-hr per day feeding schedule. The decrease in feeding was more pronounced in the animals with ventromedial hypothalamic lesions. Appetitively motivated feeding, i.e., the consumption of sweetened milk under nondeprived conditions, was als...
متن کاملCombination unilateral amygdaloid and ventromedial hypothalamic lesions: evidence for a feeding pathway.
Previous studies have reported hyperphagia and obesity in female rats with bilateral lesions of the most posterodorsal part of the amygdala. In rats with unilateral posterodorsal amygdaloid lesions, a dense pattern of anterograde degeneration appears in the ipsilateral ventromedial hypothalamus, but not the contralateral nucleus. In the present study, female rats with unilateral ventromedial hy...
متن کاملModulatory effect of ventromedial hypothalamic D2 receptors on leptin and glucose concentration
Introduction: A specific role of dopamine D2 receptor signaling of midbrain and hypothalamic dopaminergic systems has not been yet identified in energy homeostasis. Here, we investigated effects of intra-ventromedial hypothalamus (VMH) administration of the D2 receptor agonist (quinpirole) and antagonist (sulpiride) on plasma leptin and glucose levels in fasted rats. Methods: A guide cannul...
متن کاملAnand B K & Brobeck J R. Hypothalamic control of food intake in rats and cats. Yale J. Biol. Med. 24:123-40, 1951
Bilateral destructions of a well localised area in lateral hypothalamus led to complete cessation of eating, while lesions involving ventromedial nuclei or the region between these and lateral area produced hyperphagia and obesity. The lateral region (hunger mechanism) was designated 'feeding center' and the medial (inhibitory control) 'satiety center.' [The SCI indicates that this paper has be...
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ورودعنوان ژورنال:
- Journal of comparative and physiological psychology
دوره 83 1 شماره
صفحات -
تاریخ انتشار 1973